noun
a liquid or pill containing a drug that causes a person to become unconscious or extremely drowsy, often used for nefarious purposes
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The suspect was found to have used knockout drops to incapacitate his victims.
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I heard that someone slipped knockout drops into the punch at the party last night.
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Be careful at that club, there are rumors that people are putting knockout drops in drinks.
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Her beauty was like knockout drops, leaving everyone in awe.