noun
something that is not natural or normal; an abnormal state or condition
adjective
not natural; contrary to the ordinary course of nature; abnormal
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The scientist conducted experiments to study the effects of unnatural substances on plant growth.
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She thought the color of the sky looked really unnatural.
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That new dance move looks so unnatural, you gotta work on it.
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The politician's smile seemed forced and unnatural, lacking sincerity.