noun
a large, vascular organ in the abdominal cavity that filters blood, stores blood cells, and destroys old blood cells
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The spleen is an important organ responsible for filtering blood and producing antibodies.
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I heard that he injured his spleen in a skiing accident.
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She's got guts, I'll give her that, but her spleen is another story.
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His bitter spleen towards his former boss was evident in his scathing remarks.