noun
a physical discomfort or suffering caused by illness or injury
preposition
a word governing, and usually preceding, a noun or pronoun and expressing a relation to another word or element in the clause
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Dealing with constant technical issues can be a real pain in the neck in the workplace.
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My noisy neighbors are such a pain in the neck, always playing loud music late at night.
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This project is turning out to be a real pain in the neck, I can't seem to get anything right.
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Having to wait in long lines at the grocery store is a real pain in the neck.